Apolipoprotein A-II from human plasma

Forms dimers in aqueous solutions with an association constant of 5 × 10⁴ M^-1. The association is accompanied by an enhancement of ~35% in α-helical content.

Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

Solution in 10 mM ammonium bicarbonate.

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.