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Merck
CN

A1131

L-Anserine nitrate salt

≥98%

Synonym(s):

β-Ala-3-methyl-His nitrate salt, β-Alanyl-3-methyl-L-histidine nitrate salt

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About This Item

Empirical Formula (Hill Notation):
C10H16N4O3 · HNO3
CAS Number:
Molecular Weight:
303.27
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
233-079-7
MDL number:
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Product Name

L-Anserine nitrate salt, hydroxyl radical scavenger

InChI key

OLWOKAYJAHHSNY-QRPNPIFTSA-N

InChI

1S/C10H16N4O3.HNO3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11;2-1(3)4/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17);(H,2,3,4)/t8-;/m0./s1

SMILES string

O[N+]([O-])=O.Cn1cncc1C[C@H](NC(=O)CCN)C(O)=O

assay

≥98%

form

powder

color

white

application(s)

detection

Quality Level

Biochem/physiol Actions

L-Anserine s a dipeptide found in most animal tissues. In model systems it is a potent antioxidant and scavener of hydroxyl radicals. It inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars. It is much less potent than L-carnosine as an inhibitor of protein-protein crosslinking.

Other Notes

Anserine is a naturally occurring methylated analog of carnosine.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Effect of anserine ingestion on the hyperglycemia and autonomic nerves in rats and humans.
Kubomura D, Matahira Y, Nagai K, Niijima A.
Nutritional Neuroscience, 13, 1230128-1230128 (2010)
Milton Helfenstein et al.
Revista brasileira de reumatologia, 50(3), 313-327 (2010-12-03)
Knee pain is a common complaint in clinical practice, and pes anserinus tendino-bursitis syndrome (PATB) has been frequently diagnosed based only on clinical features that may cause equivocal interpretations. Patients complain of characteristic spontaneous medial knee pain with tenderness in
Daiki Kubomura et al.
Nutritional neuroscience, 13(4), 183-188 (2010-07-31)
Anserine and L-carnosine are similar dipeptides synthesized by muscles of vertebrates. The functional role of anserine is unknown, although previous studies showed hypoglycemic effects of carnosine through autonomic nerves. Thus, we evaluated the effects of anserine on blood glucose levels
Wieslaw Kopec et al.
Antioxidants (Basel, Switzerland), 9(11) (2020-11-12)
The objective of the study was to test the effect of diets supplemented with β-alanine, L-histidine, and carnosine on the histidine dipeptide content and the antioxidative status of chicken breast muscles and blood. One-day-old Hubbard Flex male chickens were assigned
Rachel S Carling et al.
Clinical chemistry and laboratory medicine, 58(5), 758-768 (2019-10-18)
Background Quantification of plasma amino acids is key to the diagnosis of inherited defects of amino acid synthesis, catabolism and transport, many of which present as clinical emergencies. The utility of this test is limited by the long analysis time

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