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Merck
CN

A1131

L-Anserine nitrate salt

≥98%

Synonym(s):

β-Ala-3-methyl-His nitrate salt, β-Alanyl-3-methyl-L-histidine nitrate salt

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About This Item

Empirical Formula (Hill Notation):
C10H16N4O3 · HNO3
CAS Number:
10030-52-1
Molecular Weight:
303.27
NACRES:
NA.26
PubChem Substance ID:
24890509
UNSPSC Code:
12352209
EC Number:
233-079-7
MDL number:
MFCD00037001

Key Documents

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Product Name

L-Anserine nitrate salt, hydroxyl radical scavenger

InChI key

OLWOKAYJAHHSNY-QRPNPIFTSA-N

InChI

1S/C10H16N4O3.HNO3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11;2-1(3)4/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17);(H,2,3,4)/t8-;/m0./s1

SMILES string

O[N+]([O-])=O.Cn1cncc1C[C@H](NC(=O)CCN)C(O)=O

assay

≥98%

form

powder

color

white

application(s)

detection

Quality Level

200

Related Categories

Biochem/physiol Actions

L-Anserine s a dipeptide found in most animal tissues. In model systems it is a potent antioxidant and scavener of hydroxyl radicals. It inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars. It is much less potent than L-carnosine as an inhibitor of protein-protein crosslinking.

Other Notes

Anserine is a naturally occurring methylated analog of carnosine.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK7850
BCCG9958
BCCD1202
BCBZ3988
BCBS9219V

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Angelo Zinellu et al.
Talanta, 84(3), 931-935 (2011-04-13)
A field amplified sample injection (FASI) capillary electrophoresis method with UV detection was developed for the separation and detection of carnosine-related peptides carnosine (Car), anserine (Ans) and homocarnosine (Hcar). The imidazole dipeptides were baseline-separated within 10 min by using 50
Verena Peters et al.
Amino acids, 42(6), 2411-2416 (2011-08-13)
Recently, we identified an allelic variant of human carnosinase 1 (CN1) that results in increased enzyme activity and is associated with susceptibility for diabetic nephropathy in humans. Investigations in diabetic (db/db) mice showed that carnosine ameliorates glucose metabolism effectively. We
Wieslaw Kopec et al.
Antioxidants (Basel, Switzerland), 9(11) (2020-11-12)
The objective of the study was to test the effect of diets supplemented with β-alanine, L-histidine, and carnosine on the histidine dipeptide content and the antioxidative status of chicken breast muscles and blood. One-day-old Hubbard Flex male chickens were assigned
Daiki Kubomura et al.
Nutritional neuroscience, 13(4), 183-188 (2010-07-31)
Anserine and L-carnosine are similar dipeptides synthesized by muscles of vertebrates. The functional role of anserine is unknown, although previous studies showed hypoglycemic effects of carnosine through autonomic nerves. Thus, we evaluated the effects of anserine on blood glucose levels
Milton Helfenstein et al.
Revista brasileira de reumatologia, 50(3), 313-327 (2010-12-03)
Knee pain is a common complaint in clinical practice, and pes anserinus tendino-bursitis syndrome (PATB) has been frequently diagnosed based only on clinical features that may cause equivocal interpretations. Patients complain of characteristic spontaneous medial knee pain with tenderness in
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