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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC
Species reactivity:
human
Citations:
10
Technique(s):
immunocytochemistry: suitable, immunohistochemistry: suitable
Uniprot accession no.:
biological source
goat
recombinant
expressed in goat
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized
mol wt
antigen 65 kDa
species reactivity
human
packaging
vial of 2 mL lyophilized antiserum
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable
UniProt accession no.
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ALB(213)
Application
Goat polyclonal anti-Albumin antiserum is used to tag albumin for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of albumin a variety of clinical indications.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin. Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease.
Goat polyclonal anti-Albumin antiserum is immunospecific for human albumin by immunoelectrophoresis against normal human serum and human albumin. Identity and purity of the specific antibody is established by immunoelectrophoresis (IEP). Electrophoresis of the antiserum followed by diffusion against anti-goat serum results in multiple arcs of precipitation, whereas against anti-goat IgG, it results in a single arc of precipitation in the γ region.
Immunogen
purified human albumin
Physical form
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
常规特殊物品
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Ryan Matsuda et al.
Journal of chromatography. A, 1416, 112-120 (2015-09-19)
A method combining on-line immunoextraction microcolumns with high-performance affinity chromatography (HPAC) was developed and tested for use in examining drug-protein interactions with normal or modified proteins. Normal human serum albumin (HSA) and glycated HSA were used as model proteins for
Elliott L Rodriguez et al.
Journal of chromatography. A, 1638, 461683-461683 (2020-11-24)
Diabetes is characterized by elevated levels of blood glucose, which can result in the modification of serum proteins. The modification of a protein by glucose, or glycation, can also lead to the formation of advanced glycated end-products (AGEs). One protein
Sadia Sharmeen et al.
Current protocols, 3(8), e867-e867 (2023-08-23)
Immunoaffinity chromatography (IAC) is a type of liquid chromatography that uses immobilized antibodies or related binding agents as selective stationary phases for sample separation or analysis. The strong binding and high selectivity of antibodies have made IAC a popular tool
Elliott L Rodriguez et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121812-121812 (2019-12-17)
An on-line purification and entrapment system was developed that could extract a protein from a sample such as serum and entrap this protein within a small column for use in high-performance affinity chromatography. Human serum albumin (HSA) was employed as
Guanglong Ma et al.
JCI insight, 9(10) (2024-05-07)
The homeostasis of IgG is maintained by the neonatal Fc receptor, FcRn. Consequently, antagonism of FcRn to reduce endogenous IgG levels is an emerging strategy for treating antibody-mediated autoimmune disorders using either FcRn-specific antibodies or an engineered Fc fragment. For
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