A131
Alprenolol hydrochloride
Synonym(s):
1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C15H23NO2 · HCl
CAS Number:
Molecular Weight:
285.81
EC Number:
237-244-4
UNSPSC Code:
41116107
MDL number:
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
SMILES string
Cl[H].CC(C)NCC(O)COc1ccccc1CC=C
InChI
1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H
InChI key
RRCPAXJDDNWJBI-UHFFFAOYSA-N
Application
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Noel Dew et al.
Colloids and surfaces. B, Biointerfaces, 89, 53-60 (2011-10-01)
To fully utilize the extended contact time of gel formulations a novel formulation with drug containing catanionic aggregates offering prolonged drug release and skin penetration were investigated. This study aimed to further explore the drug release process from catanionic vesicles
Marjukka Ikonen et al.
Colloids and surfaces. B, Biointerfaces, 78(2), 275-282 (2010-04-20)
In this work, isothermal titration calorimetry (ITC) combined with zeta potential measurements was used to study the binding and partitioning of three beta-blockers, alprenolol, labetalol and propranolol, and the local anaesthetic tetracaine into liposomes. The thermodynamic parameters of enthalpy, entropy
Naoya Kishikawa et al.
Journal of chromatography. A, 1218(20), 3002-3006 (2011-04-15)
A novel fluorescent labeling method for alprenolol was developed based on Mizoroki-Heck coupling reaction. We designed and synthesized fluorescent aryl iodide, 4-(4,5-diphenyl-1H-imidazol-2-yl)iodobenzene (DIBI) as a labeling reagent. DIBI has a lophine skeleton carrying an iodide atom acting as fluorophore and
Xiaogang Hu et al.
Journal of chromatography. A, 1216(2), 190-197 (2008-12-17)
An improved multiple co-polymerization technique was developed to prepare a novel molecularly imprinted polymer (MIP)-coated solid-phase microextraction (SPME) fiber with propranolol as template. Investigation was performed for the characteristics and application of the fibers. The MIP coating was highly crosslinked
Maki Mizogami et al.
European journal of anaesthesiology, 27(9), 829-834 (2010-07-06)
beta-Adrenoceptor-blocking agents have been used for perioperative management during anaesthesia, in which selective beta1-blockers are advantageous over nonselective beta-blockers. Apart from the different affinity for beta-adrenoceptors, beta1-blockers were differentially characterized in light of their different interaction with lipid membranes. Selective
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