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Merck
CN

A131

Alprenolol hydrochloride

Synonym(s):

1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C15H23NO2 · HCl
CAS Number:
Molecular Weight:
285.81
EC Number:
237-244-4
UNSPSC Code:
41116107
MDL number:
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InChI key

RRCPAXJDDNWJBI-UHFFFAOYSA-N

InChI

1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H

SMILES string

Cl[H].CC(C)NCC(O)COc1ccccc1CC=C

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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Marjukka Ikonen et al.
Colloids and surfaces. B, Biointerfaces, 78(2), 275-282 (2010-04-20)
In this work, isothermal titration calorimetry (ITC) combined with zeta potential measurements was used to study the binding and partitioning of three beta-blockers, alprenolol, labetalol and propranolol, and the local anaesthetic tetracaine into liposomes. The thermodynamic parameters of enthalpy, entropy
Naoya Kishikawa et al.
Journal of chromatography. A, 1218(20), 3002-3006 (2011-04-15)
A novel fluorescent labeling method for alprenolol was developed based on Mizoroki-Heck coupling reaction. We designed and synthesized fluorescent aryl iodide, 4-(4,5-diphenyl-1H-imidazol-2-yl)iodobenzene (DIBI) as a labeling reagent. DIBI has a lophine skeleton carrying an iodide atom acting as fluorophore and
Harri Härmä et al.
Journal of biomolecular screening, 14(8), 936-943 (2009-08-18)
In this article, a single-label separation-free fluorescence technique is presented as a potential screening method for cell-based receptor antagonists and agonists.The time-resolved fluorescence technique, quenching resonance energy transfer (QRET), relies on a single-labeled binding partner in combination with a soluble
Olga Escanilla et al.
The European journal of neuroscience, 32(3), 458-468 (2010-07-14)
The mammalian main olfactory bulb (MOB) receives a significant noradrenergic input from the locus coeruleus. Norepinephrine (NE) is involved in the acquisition of conditioned odor preferences in neonatal animals and in some species-specific odor-dependent behaviors. Thus far, the role of
Noel Dew et al.
Colloids and surfaces. B, Biointerfaces, 70(2), 187-197 (2009-01-27)
The aim of this study was to explore if mixtures of drug containing catanionic vesicles and polymers give rise to gel formation, and if so, if drug release from these gels could be prolonged. Catanionic vesicles formed from the drug

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