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Merck
CN

A1556

15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum

mycotoxin, powder

Synonym(s):

15-Acetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one

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About This Item

Empirical Formula (Hill Notation):
C17H22O7
CAS Number:
Molecular Weight:
338.35
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
powder
Quality level:
Technical Service
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Product Name

15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum,

form

powder

Quality Level

storage temp.

2-8°C

SMILES string

CC(=O)OC[C@]12[C@H](O)C(=O)C(C)=C[C@H]1O[C@@H]3[C@H](O)C[C@@]2(C)[C@]34CO4

InChI

1S/C17H22O7/c1-8-4-11-16(6-22-9(2)18,13(21)12(8)20)15(3)5-10(19)14(24-11)17(15)7-23-17/h4,10-11,13-14,19,21H,5-7H2,1-3H3/t10-,11-,13-,14-,15-,16-,17+/m1/s1

InChI key

IDGRYIRJIFKTAN-HTJQZXIKSA-N

General description

15-O-Acetyl-4-deoxynivalenol (15-ADON) is a member of type B trichothecene mycotoxin. It is found abundantly in fungi of Fusarium genus growing on cereals such as oats, wheat, rye, maize, and barley.

Application

15-O-Acetyl-4-deoxynivalenol (15-ADON) has been used as a trichothecene compound to treat wheat ovaries for doubled haploid subpopulations studies.

Biochem/physiol Actions

15-O-Acetyl-4-deoxynivalenol (15-ADON) can be harmful for the consumption of humans and livestock.


pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

高风险级别生物产品--毒素类产品

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Trichothecene-mediated in vitro selection in wheat for reduced mycotoxin accumulation caused by Fusarium graminearum
Eudes F, et al.
Canadian Journal of Plant Science , 88(6), 1115-1125 (2008)
Helle Katrine Knutsen et al.
EFSA journal. European Food Safety Authority, 15(9), e04718-e04718 (2017-09-11)
Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring predominantly in cereal grains. Following the request of the European Commission, the CONTAM Panel assessed the risk to animal and human health related to DON, 3-acetyl-DON (3-Ac-DON), 15-acetyl-DON (15-Ac-DON) and
Pianpian Yan et al.
Toxins, 12(3) (2020-04-03)
Deoxynivalenol (DON), along with 3-acetyl-deoxynivalenol (3-ADON) and 15-acetyl-deoxynivalenol (15-ADON), occur in grains and cereal products and is often hazardous to humans and livestock. In this study, 579 wheat samples and 606 maize samples intended for consumption were collected from China



Global Trade Item Number

SKUGTIN
A1556-1MG04061833342466
A1556-5MG04061832938400