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A1556

15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum

Name: 15-<I>O</I>-Acetyl-4-deoxynivalenol from <I>Fusarium graminearum</I>
Brand: SIGMA

mycotoxin, powder

Synonym(s):

15-Acetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₂O₇

CAS Number:

88337-96-6

Molecular Weight:

338.35

UNSPSC Code:

12352116

PubChem Substance ID:

24890561

NACRES:

NA.77

MDL number:

MFCD00083218

Form:

powder

Quality level:

200

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Product Name

15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum,

form

powder

Quality Level

200

storage temp.

2-8°C

SMILES string

CC(=O)OC[C@]12[C@H](O)C(=O)C(C)=C[C@H]1O[C@@H]3[C@H](O)C[C@@]2(C)[C@]34CO4

InChI

1S/C17H22O7/c1-8-4-11-16(6-22-9(2)18,13(21)12(8)20)15(3)5-10(19)14(24-11)17(15)7-23-17/h4,10-11,13-14,19,21H,5-7H2,1-3H3/t10-,11-,13-,14-,15-,16-,17+/m1/s1

InChI key

IDGRYIRJIFKTAN-HTJQZXIKSA-N

Related Categories

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

General description

15-O-Acetyl-4-deoxynivalenol (15-ADON) is a member of type B trichothecene mycotoxin. It is found abundantly in fungi of Fusarium genus growing on cereals such as oats, wheat, rye, maize, and barley.

Application

15-O-Acetyl-4-deoxynivalenol (15-ADON) has been used as a trichothecene compound to treat wheat ovaries for doubled haploid subpopulations studies.

Biochem/physiol Actions

15-O-Acetyl-4-deoxynivalenol (15-ADON) can be harmful for the consumption of humans and livestock.

pictograms

GHS06

signalword

Danger

hcodes

H300,H311 + H331

pcodes

P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

高风险级别生物产品--毒素类产品

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Certificates of Analysis (COA)

Lot/Batch Number

0000299619

0000299618

0000284641

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Trichothecene-mediated in vitro selection in wheat for reduced mycotoxin accumulation caused by Fusarium graminearum

Eudes F, et al.

Canadian Journal of Plant Science , 88(6), 1115-1125 (2008)

Risks to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed.

Helle Katrine Knutsen et al.

EFSA journal. European Food Safety Authority, 15(9), e04718-e04718 (2017-09-11)

Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring predominantly in cereal grains. Following the request of the European Commission, the CONTAM Panel assessed the risk to animal and human health related to DON, 3-acetyl-DON (3-Ac-DON), 15-acetyl-DON (15-Ac-DON) and

Natural Occurrence of Deoxynivalenol and Its Acetylated Derivatives in Chinese Maize and Wheat Collected in 2017.

Pianpian Yan et al.

Toxins, 12(3) (2020-04-03)

Deoxynivalenol (DON), along with 3-acetyl-deoxynivalenol (3-ADON) and 15-acetyl-deoxynivalenol (15-ADON), occur in grains and cereal products and is often hazardous to humans and livestock. In this study, 579 wheat samples and 606 maize samples intended for consumption were collected from China

Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens.

H V L N Swamy et al.

Poultry science, 83(4), 533-543 (2004-04-28)

An experiment was conducted to investigate the effects of feeding grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens. Three hundred sixty, 1-d-old male broiler chicks were fed 1 of 4 diets containing grains naturally

Trichothecene genotypes and chemotypes in Fusarium graminearum strains isolated from wheat in Argentina.

María Marta Reynoso et al.

International journal of food microbiology, 145(2-3), 444-448 (2011-02-16)

Argentina is the fourth largest exporter of wheat in the world. The main pathogen associated with Fusarium Head Blight (FHB) of wheat in Argentina is Fusarium graminearum lineage 7 also termed F. graminearum sensu stricto in the F. graminearum species

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Global Trade Item Number

SKU	GTIN
A1556-1MG	04061833342466
A1556-5MG	04061832938400

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