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A1852

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

Name: Adenosine 5&#8242;-triphosphate (ATP) disodium salt hydrate
Brand: SIGMA

≥99% (HPLC), microbial (Corynebacterium sp.), powder

Synonym(s):

ATP disodium hydrate

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About This Item

Linear Formula:

C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O

CAS Number:

34369-07-8

Molecular Weight:

551.14 (anhydrous basis)

UNSPSC Code:

41106305

eCl@ss:

32160414

PubChem Substance ID:

24890593

EC Number:

213-579-1

NACRES:

NA.51

MDL number:

MFCD00150755

Assay:

≥99% (HPLC)

Biological source:

microbial (Corynebacterium sp.)

Form:

powder

Solubility:

water: 50 mg/mL, clear, colorless

Storage temp.:

−20°C

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Product Name

Adenosine 5′-triphosphate (ATP) disodium salt hydrate, vial of 30 mg

biological source

microbial (Corynebacterium sp.)

Quality Level

200

assay

≥99% (HPLC)

form

powder

packaging

vial of 30 mg

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

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Related Categories

Biochemicals

Nucleosides and Nucleotides

Phosphates

General description

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger CAMP. ATP provides the metabolic energy to drive metabolic pumps.

Application

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been used:

in rat hippocampal slice cultures to mimic synaptic signalling
in the isolation of plasmid from primary porcine alveolar macrophages (PAMs)
as a component of hot reaction kinase buffer for in gel kinase assay

ATP serves as a coenzyme in a wide array of enzymatic reactions.Adenosine 5′-triphosphate (ATP) disodium salt hydrate is used for tissue preparation and maintenance.

Biochem/physiol Actions

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

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Resistance to water diffusion in the stratum corneum is depth-dependent.

Mark D A van Logtestijn et al.

PloS one, 10(2), e0117292-e0117292 (2015-02-12)

The stratum corneum (SC) provides a permeability barrier that limits the inflow and outflow of water. The permeability barrier is continuously and dynamically formed, maintained, and degraded along the depth, from the bottom to the top, of the SC. Naturally

Bio-Protocol

Pizzio GA and Rodriguez PL

Testing, 7(5) (2017)

NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination

Park HS, et al.

Journal of Virology, JVI-00022 (2018)

N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia.

JuanJuan Duan et al.

Cellular signalling, 58, 44-52 (2019-03-12)

Persistent inflammasome activation contributes to chronic, low grade inflammation. However, it is unclear how the inflammasome activation is sustained after initiation. Here we reported that N4-acetylcytidine (N4A), a nucleoside metabolite, activated microglia and sustained NLRP3 inflammasome activation by inducing HMGB1

Potential Role of Extracellular ATP Released by Bacteria in Bladder Infection and Contractility.

Behnam Abbasian et al.

mSphere, 4(5) (2019-09-06)

Urgency urinary incontinence (UUI) and overactive bladder (OAB) can both potentially be influenced by commensal and urinary tract infection-associated bacteria. The sensing of bladder filling involves interplay between various components of the nervous system, eventually resulting in contraction of the

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Global Trade Item Number

SKU	GTIN
A1852-1VL	04061835514908

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