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Merck
CN

A1900

Sigma-Aldrich

Albumin, Monomer bovine

Monomer ≥97 %

Synonym(s):

Albumin powder, Bovine albumins

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.26
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biological source

bovine

Assay

≥97% (PAGE)

form

lyophilized powder

composition

Monomer, ≥97%

technique(s)

SDS-PAGE: suitable

solubility

H2O: soluble 50 mg/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

bovine ... ALB(280717)

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

Application

Albumin, Monomer bovine has been used as a:
  • molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops
  • standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration
  • model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies

The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.

Preparation Note

Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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John P O'Donnell et al.
Methods in molecular biology (Clifton, N.J.), 2159, 93-113 (2020-06-13)
A common feature of dynamin-related proteins (DRPs) is their use of guanosine triphosphate (GTP) to control protein dynamics. In the case of the endoplasmic- reticulum- (ER)-resident membrane protein atlastin (ATL), GTP binding and hydrolysis result in membrane fusion of ER
Ming-Yuan Su et al.
Nature communications, 8(1), 1516-1516 (2017-11-16)
Peptidoglycan (PG) is a highly cross-linked, protective mesh-like sacculus that surrounds the bacterial cytoplasmic membrane. Expansion of PG is tightly coupled to growth of a bacterial cell and requires hydrolases to cleave the cross-links for insertion of nascent PG material.
Sarita Aryal et al.
Biomolecules, 10(9) (2020-08-30)
In Trichomonas vaginalis (T. vaginalis), cyclophilins play a vital role in dislodging Myb proteins from the membrane compartment and leading them to nuclear translocation. We previously reported that TvCyP1 cyclophilin from T. vaginalis forms a dimer and plays an essential
Piramon Hampitak et al.
ACS sensors, 5(11), 3520-3532 (2020-10-27)
We present a sensitive and low-cost immunoassay, based on a customized open-source quartz crystal microbalance coupled with graphene biointerface sensors (G-QCM), to quantify antibodies in undiluted patient serum. We demonstrate its efficacy for a specific antibody against the phospholipase A2
Pasquale Aragona et al.
Translational vision science & technology, 8(6), 2-2 (2019-11-07)
To assess the physicochemical properties of hyaluronic acid (HA)-based artificial tears. The average molecular weight (MW) and polydispersion index (PDI) of HA in 18 commercially available artificial tears were determined by light scattering/high-performance liquid chromatography. Osmolality, pH, viscosity, and sodium

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