A2142
N-Acetyl-α-D-glucosamine 1-phosphate disodium salt
≥95% (TLC)
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About This Item
Linear Formula:
C8H14NO9PNa2
CAS Number:
Molecular Weight:
345.15
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25
Quality Level
Assay
≥95% (TLC)
form
powder
impurities
≤9% water (Karl Fischer)
color
white
solubility
water: 50 mg/mL, clear, colorless
cation traces
Na: 10.0-14.0% (Dry basis)
P: 8.0-9.6% (dry basis)
storage temp.
−20°C
SMILES string
[Na].CC(=O)NC1C(O)C(O)C(CO)OC1OP(O)(O)=O
InChI
1S/C8H16NO9P.Na.H/c1-3(11)9-5-7(13)6(12)4(2-10)17-8(5)18-19(14,15)16;;/h4-8,10,12-13H,2H2,1H3,(H,9,11)(H2,14,15,16);;
InChI key
VFEAQNOAPUQCLS-UHFFFAOYSA-N
General description
N-Acetyl-D-glucosamine 1-phosphate (GlcNAc-1P) acts as a substrate for UDP-GlcNAc pyrophosphorylase to synthesize UDP-GlcNAc in the presence of UTP. GlcNAc-1P is a product of reverse pyrophosphorolysis of UDP-GlcNAc catalyzed by UDP-GlcNAc pyrophosphorylase.
Application
N-Acetyl-α-D-glucosamine 1-phosphate disodium salt has been used as a component of substrate solution for nucleotide triphosphate (NTP) transferases.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor
Raimi OG, et al.
RSC medicinal chemistry, 1(1), 13-25 (2020)
Alexandra Deli et al.
The FEBS journal, 277(13), 2740-2753 (2010-05-25)
The genomes of Bacillus cereus and its closest relative Bacillus anthracis each contain two LmbE protein family homologs: BC1534 (BA1557) and BC3461 (BA3524). Only a few members of this family have been biochemically characterized including N-acetylglucosaminylphosphatidyl inositol (GlcNAc-PI), 1-D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins)
Measurement of Nucleotide Triphosphate Sugar Transferase Activity via Generation of Pyrophosphate
Maeda K, et al.
2013 Nurse's Drug Handbook, 5(8), e1450-e1450 (2015)
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