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A2729

Amisulpride

Name: Amisulpride
Brand: SIGMA

≥98% (HPLC), D2/D3 dopamine receptor antagonist , powder

Synonym(s):

4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide, DAN-2163, Deniban

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₇N₃O₄S

CAS Number:

71675-85-9

Molecular Weight:

369.48

NACRES:

NA.77

PubChem Substance ID:

24890689

UNSPSC Code:

12352200

EC Number:

275-831-7

MDL number:

MFCD00866691

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated, protect from light

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Properties

Product Name

Amisulpride, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated, protect from light

color

white

originator

Sanofi Aventis

storage temp.

2-8°C

SMILES string

O=C(NCC1CCCN1CC)C2=CC(S(=O)(CC)=O)=C(N)C=C2OC

InChI

1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)

InChI key

NTJOBXMMWNYJFB-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR6(3362), HTR7(3363)

Description

Application

Amisulpride has been used as a dopamine receptor inhibitor to study its effects on diabetic bone abnormalities in mice.

Biochem/physiol Actions

Amisulpride is a substituted benzamide derivative. It has a higher affinity towards dopamine receptors in limbic structures than the striatal structures. Amisulpride has a therapeutic effect against schizophrenia.

Amisulpride is a highly selective D₂/D₃ dopamine receptor antagonist and atypical antipsychotic.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c