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Merck
CN

A3097

[Pro18, Asp21]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

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About This Item

Empirical Formula (Hill Notation):
C33H43N5O8
CAS Number:
Molecular Weight:
637.72
UNSPSC Code:
12352200
MDL number:
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assay

≥98% (HPLC)

form

solid

UniProt accession no.

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O

Gene Information

human ... APP(351)

Biochem/physiol Actions

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.
Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.


Regulatory Information

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