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A3903

1-Aminocyclopropanecarboxylic acid

Name: 1-Aminocyclopropanecarboxylic acid
Brand: SIGMA

≥98% (TLC), powder, NMDA agonist

Synonym(s):

ACC, ACPC

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About This Item

Empirical Formula (Hill Notation):

C₄H₇NO₂

CAS Number:

22059-21-8

Molecular Weight:

101.10

NACRES:

NA.32

PubChem Substance ID:

24890826

UNSPSC Code:

12352209

MDL number:

MFCD00009944

Beilstein/REAXYS Number:

2076413

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

Storage condition:

(Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place.)

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Product Name

1-Aminocyclopropanecarboxylic acid, ≥98% (TLC), powder

Quality Level

200

assay

≥98% (TLC)

form

powder

storage condition

(Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place.)

color

white

mp

229-231 °C (lit.)

solubility

water: 49.00-51.00 mg/mL, clear, colorless

SMILES string

NC1(CC1)C(O)=O

InChI

1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)

InChI key

PAJPWUMXBYXFCZ-UHFFFAOYSA-N

Gene Information

human ... NARG2(79664)
mouse ... NARG2(93697)
rat ... LOC686240(686240), NARG2(691379)

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Related Categories

Bioactive Small Molecules

General description

Research area: Cell Signaling

1-Aminocyclopropanecarboxylic acid (ACC) is a non-proteinogenic amino acid and is a member of 1-aminocycloalkanecarboxylic acids.

Application

1-Aminocyclopropanecarboxylic acid (ACC) has been used as a substrate for determining ACC deaminase activity to study the plant growth-promoting characteristics of endophytic isolates obtained from Pteris vittata roots, cucurbit seeds. It has also been used as an ethylene precursor to study the effect of high ethylene concentration on lateral root density (LRD) in sorghum brown midrib (bmr) mutants.

Biochem/physiol Actions

1-Aminocyclopropanecarboxylic acid (ACC) is a partial agonist acting at the N-methyl-D-aspartate (NMDA) receptor glycine modulatory site. ACC serves as a bio-synthetic precursor for the plant hormone ethylene. Therefore, it also plays a vital role in plant development. ACC exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

农药列管产品

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1-Aminocyclopropanecarboxylic acid (ACPC) produces procognitive but not antipsychotic-like effects in rats

Popik P, et al.

Psychopharmacology, 232(6), 1025?1038-1025?1038 (2000)

Stress- and pathway-specific impacts of impaired jasmonoyl-isoleucine (JA-Ile) catabolism on defense signalling and biotic stress resistance.

Valentin Marquis et al.

Plant, cell & environment, 43(6), 1558-1570 (2020-03-13)

Jasmonate synthesis and signalling are essential for plant defense upregulation upon herbivore or microbial attacks. Stress-induced accumulation of jasmonoyl-isoleucine (JA-Ile), the bioactive hormonal form triggering transcriptional changes, is dynamic and transient because of the existence of potent removal mechanisms. Two

Identification of arsenic resistant endophytic bacteria from Pteris vittata roots and characterization for arsenic remediation application.

Sarita Tiwari et al.

Journal of environmental management, 180, 359-365 (2016-06-04)

Mitigation of arsenic (As) pollution is a topical environmental issue of high R&D priority. The present investigation was carried out to isolate As resistant endophytes from the roots of Indian ecotype Pteris vittata and characterize their As transformation and tolerance

1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance.

Y A Kolesnikov et al.

Life sciences, 55(18), 1393-1398 (1994-01-01)

1-Aminocyclopropane carboxylic acid (ACPC), a partial agonist of the glycine site on the NMDA receptor, prevents tolerance to the mu opioid morphine and the delta ligand [D-Pen2,D-Pen5]enkephalin (DPDPE) when co-administered with the opioid. In contrast, ACPC does not significantly influence

Conformational profile of 1-aminocyclopropanecarboxylic acid

Catalan JG, et al.

Theoretical Chemistry Accounts, 380-389 (2000)

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Global Trade Item Number

SKU	GTIN
A3903-100MG	04061833368213
A3903-250MG	04061833368237
A3903-1G	04061833368220

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