A4339
N-Acetyl-Tyr-Val-Lys(biotinyl)-Asp 2,6-dimethylbenzoyloxymethyl ketone
≥90% (HPLC), powder
Synonym(s):
Ac-YVK(biotinyl)D 2,6-dimethylbenzoyloxymethyl ketone
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About This Item
Empirical Formula (Hill Notation):
C46H63N7O12S
CAS Number:
Molecular Weight:
938.10
UNSPSC Code:
12352209
NACRES:
NA.77
MDL number:
Product Name
N-Acetyl-Tyr-Val-Lys(biotinyl)-Asp 2,6-dimethylbenzoyloxymethyl ketone, ≥90% (HPLC), powder
assay
≥90% (HPLC)
form
powder
solubility
DMF: 1 mg/mL
storage temp.
−20°C
Quality Level
Application
Useful for affinity labeling the larger subunit of activated caspase 1 and caspase 1 related proteases.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Dodheri Syed Samiulla et al.
Organic and medicinal chemistry letters, 2(1), 27-27 (2012-07-17)
Caspase-3 inhibition has been demonstrated to be therapeutically effective in moderating excessive programmed cell death. Interest in caspase-3 as a therapeutic target has led many to pursue the development of inhibitors. To date, only a few series of non-peptide inhibitors
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