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A4599

L-Arginine monohydrochloride

Name: <SC>L</SC>-Arginine monohydrochloride
Brand: SIGMA

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Synonym(s):

(S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride

Empirical Formula (Hill Notation):

C₆H₁₄N₄O₂ · HCl

CAS Number:

1119-34-2

Molecular Weight:

210.66

Beilstein:

3631658

EC Number:

214-275-1

MDL number:

MFCD00064550

NACRES:

NA.26

biological source

non-animal source

Quality Level

400

Assay

≥98.5%

form

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, residual solvents, tested

solubility

H₂O: 100 mg/mL

density

1.42 g/cm³ at 20 °C

anion traces

chloride (Cl^-): 16.58-17.00%
sulfate (SO₄^2-): ≤0.020%

cation traces

As: ≤1.0 ppm
NH₄⁺: ≤0.02%
heavy metals: ≤10 ppm

application(s)

pharmaceutical (small molecule)

foreign activity

cytotoxicity, tested

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

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Upstream Process Chemicals

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

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Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

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Application

L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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