A5282
DL-2-Amino-5-phosphonopentanoic acid
≥98% (TLC), solid, NMDA receptor antagonist
Synonym(s):
5-Phosphono-DL-norvaline, DL-2-Amino-5-phosphonovaleric acid, AP-5, APV
About This Item
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Product Name
DL-2-Amino-5-phosphonopentanoic acid, solid
form
solid
color
white
solubility
0.1 M NaOH: 4 mg/mL
H2O: 5.6 mg/mL
organic solvents: insoluble
SMILES string
NC(CCCP(O)(O)=O)C(O)=O
InChI
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChI key
VOROEQBFPPIACJ-UHFFFAOYSA-N
Gene Information
rat ... Grik1(29559), Grin2a(24409), Grin2b(24410)
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This Item | 27508 | 27509 | 27505U |
|---|---|---|---|
| feature closure type black phenolic solid top cap, closure type screw top vial | feature closure type black phenolic solid top cap, closure type screw top vial | feature closure type black phenolic solid top cap, closure type screw top vial | feature closure type black phenolic solid top cap, closure type screw top vial |
| volume 7 mL | volume 15 mL | volume 22 mL | volume 2 mL |
| material PTFE liner, clear glass vial, black phenolic solid cap | material PTFE liner, black phenolic solid cap, clear glass vial | material PTFE liner, black phenolic solid cap, clear glass vial | material PTFE liner, black phenolic solid cap, clear glass vial |
| fitting thread for 15-425 | fitting thread for 18-400 | fitting thread for 20-400 | fitting thread for 8-425 |
| packaging pkg of 100 ea | packaging pkg of 100 ea | packaging pkg of 100 ea | packaging pkg of 100 ea |
| O.D. × H 17 mm × 60 mm | O.D. × H 21 mm × 70 mm | O.D. × H 23 mm × 85 mm | O.D. × H - |
Application
- in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses[1]
- used in growth medium for inhibition of electrical activity in the neuronal network[2]
- used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product[3]
- used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)[4]
Biochem/physiol Actions
Caution
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Regulatory Information
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