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A5456

NOC-5

Name: NOC-5
Brand: SIGMA

≥90%, powder

Synonym(s):

3-(Aminopropyl)-1-hydroxy-3-isopropyl-2-oxo-1-triazene

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₆N₄O₂

CAS Number:

146724-82-5

Molecular Weight:

176.22

UNSPSC Code:

12352204

PubChem Substance ID:

24890974

NACRES:

NA.32

MDL number:

MFCD00274389

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Product Name

NOC-5, ≥90%

Quality Level

100

assay

≥90%

form

powder

solubility

methanol: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC(C)N(CCCN)\[N+]([O-])=N\O

InChI

1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,11H,3-5,7H2,1-2H3/b10-8-

InChI key

MTIRIKBRVALRPJ-NTMALXAHSA-N

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Application

Releases nitric oxide spontaneously in a rate-controlled manner; half life in solution = 93 min.

signalword

Danger

Hazard Classifications

Self-react. C

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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A Promiscuous Cytochrome P450 Hydroxylates Aliphatic and Aromatic C-H Bonds of Aromatic 2,5-Diketopiperazines.

Guangde Jiang et al.

Chembiochem : a European journal of chemical biology, 20(8), 1068-1077 (2019-01-04)

Cytochrome P450 enzymes generally functionalize inert C-H bonds, and thus, they are important biocatalysts for chemical synthesis. However, enzymes that catalyze both aliphatic and aromatic hydroxylation in the same biotransformation process have rarely been reported. A recent biochemical study demonstrated

Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress.

Joana Schuelter Boeing et al.

Food chemistry, 220, 427-437 (2016-11-20)

Bactris setosa Mart. is a Brazilian tree from the palm family (Arecaceae), whose fruits are scientifically underexploited. Here, we report, for the first time, the identification and quantification of phenolic compounds and carotenoids in the pulp, seed, and peel extracts

Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D.

Lucie Valek et al.

Redox biology, 20, 217-235 (2018-10-28)

Upregulations of neuronal nitric oxide synthase (nNOS) in the rodent brain have been associated with neuronal aging. To address underlying mechanisms we generated SH-SY5Y neuronal cells constitutively expressing nNOS at a level similar to mouse brain (nNOS+ versus MOCK). Initial

Hrabie, J.A., et al.

The Journal of Organic Chemistry, 58, 1472-1472 (1993)

Influence of coffee genotype on bioactive compounds and the in vitro capacity to scavenge reactive oxygen and nitrogen species.

Naira Poerner Rodrigues et al.

Journal of agricultural and food chemistry, 63(19), 4815-4826 (2015-04-25)

The influence of green coffee genotype on the bioactive compounds and the in vitro antioxidant capacity against the principal reactive oxygen (ROO(•), H2O2, HO(•), and HOCl) and nitrogen (NO(•) and ONOO(-)) species of biological relevance was investigated. This is the

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Articles

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

感应染料

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

Global Trade Item Number

SKU	GTIN
A5456-10MG	04061833375907

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