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Merck
CN

A5665

Adenine

BioReagent, suitable for plant cell culture, ≥99%

Synonym(s):

6-Aminopurine, Vitamin B4

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About This Item

Empirical Formula (Hill Notation):
C5H5N5
CAS Number:
73-24-5
Molecular Weight:
135.13
UNSPSC Code:
10171502
NACRES:
NA.72
PubChem Substance ID:
24891010
EC Number:
200-796-1
Beilstein/REAXYS Number:
5777
MDL number:
MFCD00041790

Key Documents

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Product Name

Adenine, BioReagent, suitable for plant cell culture, ≥99%

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

SMILES string

Nc1ncnc2[nH]cnc12

product line

BioReagent

assay

≥99%

form

powder

mol wt

Mw 135.13 g/mol

technique(s)

cell culture | plant: suitable

color

white to off-white

mp

>360 °C (lit.)

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

application(s)

agriculture

Quality Level

200

Gene Information

human ... AKT1(207), GSK3B(2932), LCK(3932), MAP3K1(4214), MAPK14(1432), MAPK8(5599), MAPK9(5601), MAPKAPK2(9261), PRKACA(5566), PRKCA(5578), RAF1(5894), ROCK2(9475)
mouse ... Mapk1(26413)
rat ... Camk2a(25400), Mapk10(25272)

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Application

Adenine has been used in yeast extract supplemented (YES) broth and yeast nitrogen base glutamate (YNG)l media.
Adenine may be used as a plant cell culture additive. Adenine Sulphate (25mg/L) in the culture media such as Murashige & Skoog media improves the frequency of multiple shoot production and recovered the chlorotic symptoms of the leaves.

General description

Adenine (Ade) is a purine base, which is present in nucleic acids. It binds with ribose to form nucleoside adenosine (A) and attach to deoxyribose to form nucleoside deoxyadenosine (dA).

Hazard Classifications

Acute Tox. 3 Oral

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000477412
0000477411
0000477411
0000477412
0000463584

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Adenine
Encyclopedia of Genetics (2001)
Single-step marker switching in Schizosaccharomyces pombe using a lithium acetate transformation protocol
Brown S D and Lorenz A
Bio-protocol, 6(24) (2016)
Didier Wion et al.
Nature reviews. Microbiology, 4(3), 183-192 (2006-02-21)
N(6)-methyl-adenine is found in the genomes of bacteria, archaea, protists and fungi. Most bacterial DNA adenine methyltransferases are part of restriction-modification systems. Certain groups of Proteobacteria also harbour solitary DNA adenine methyltransferases that provide signals for DNA-protein interactions. In gamma-proteobacteria
Ravindra K Gupta et al.
The Journal of infectious diseases, 207 Suppl 2, S101-S106 (2013-05-25)
Recent data from studies on treatment as prevention (TasP) and preexposure prophylaxis (PrEP) show that antiretroviral drugs can be used in prevention, as well as in treatment. The movement from first-generation antiretroviral therapy (ART) coformulations based on thymidine analogues to
Georg Behrens et al.
AIDS patient care and STDs, 28(4), 168-175 (2014-03-26)
The once daily, single-tablet regimen (STR) combining rilpivirine (RPV), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) provides a simplified treatment option for antiretroviral therapy (ART)-naïve patients with baseline HIV-1 RNA (BLVL) of ≤100,000 copies/mL. The aim of this analysis is
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