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Merck
CN

A6757

D-Arginine monohydrochloride

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
Molecular Weight:
210.66
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-010-1
MDL number:
Beilstein/REAXYS Number:
5773432
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Product Name

D-Arginine monohydrochloride, ≥98% (TLC)

assay

≥98% (TLC)

form

powder

color

white

mp

216-218 °C

application(s)

cell analysis
peptide synthesis

SMILES string

Cl.N[C@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m1./s1

InChI key

KWTQSFXGGICVPE-PGMHMLKASA-N

Application

D-arginine attenuates increased arginase expression, oxidative stress, endothelial dysfunction, and advanced glycation endproducts formation induced by methylgloxyl and high glucose. This attenuation by D-arginine is thought to occur through an endothelial NOS independent mechanism.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Phuong V Tran et al.
Biochemical and biophysical research communications, 533(4), 965-970 (2020-10-04)
Central administration of L-arginine was reported to attenuate stress responses in neonatal chicks. The present study aimed to elucidate the differential effects of centrally administered L-arginine and its enantiomer, D-arginine, on the stress response in chicks and the associated mechanisms.
D-arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an eNOS-independent mechanism
Dahr, I., et al.
Journal of Pharmacology and Experimental Therapeutics, 63, 196-204 (2012)
A simple method of preparing D-(minus)-arginine monohydrochloride from DL-arginine.
C P Berg et al.
Analytical biochemistry, 63(1), 68-72 (1975-01-01)



Global Trade Item Number

SKUGTIN
A6757-5G04061832720548
A6757-1G04061826210635