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A6933

Acetyl-Amyloid β-Protein Fragment 15-20 Amide

Name: Acetyl-Amyloid β-Protein Fragment 15-20 Amide
Brand: SIGMA

≥97% (HPLC), powder

Synonym(s):

Ac-QKLVFF-NH₂, amyloid blocker

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About This Item

Empirical Formula (Hill Notation):

C₄₂H₆₃N₉O₈

CAS Number:

189064-06-0

Molecular Weight:

822.01

NACRES:

NA.32

PubChem Substance ID:

329770908

UNSPSC Code:

12352202

MDL number:

MFCD17215285

Form:

powder

Assay:

≥97% (HPLC)

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Properties

Quality Segment

200

assay

≥97% (HPLC)

form

powder

color

white

UniProt accession no.

P05067

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C(N)=O

InChI

1S/C42H63N9O8/c1-25(2)22-33(49-38(55)30(18-12-13-21-43)47-39(56)31(46-27(5)52)19-20-35(44)53)41(58)51-36(26(3)4)42(59)50-34(24-29-16-10-7-11-17-29)40(57)48-32(37(45)54)23-28-14-8-6-9-15-28/h6-11,14-17,25-26,30-34,36H,12-13,18-24,43H2,1-5H3,(H2,44,53)(H2,45,54)(H,46,52)(H,47,56)(H,48,57)(H,49,55)(H,50,59)(H,51,58)/t30-,31-,32-,33-,34-,36-/m0/s1

InChI key

DDXTVYDSGCHGAN-PITCCTKHSA-N

Gene Information

human ... APP(351)

Description

Biochem/physiol Actions

Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

067H0822

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Global Trade Item Number

SKU	GTIN
A6933-1MG	04061826671047