A7003
Alginic acid from brown algae
powder
Synonym(s):
Alginic acid from Macrocystis pyrifera (kelp), Mixed polymer of mannuronic and guluronic acid
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About This Item
Linear Formula:
(C6H8O6)n
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47
form
powder
Quality Level
technique(s)
titration: suitable
color
white to light yellow
pH range
1.5-3.5
mp
300 °C
solubility
H2O: insoluble, but swells
aqueous base: soluble
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
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General description
Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae. It is reported to inhibit the reverse transcriptase activity of HIV. Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported. Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported. Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported. It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).
Application
Alginic acid is suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates. It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.
Other Notes
A straight-chain, hydrophilic, colloidal, polyuronic acid composed primarily of anhydro-β-D-mannuronic acid residues with 1→4 linkage.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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K C S Queiroz et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(5), 303-307 (2008-05-06)
Brown algae have two kinds of acid polysaccharides present in the extracellular matrix: sulfated fucan and alginic acid. We have previously isolated and characterized fucans from several species of brown seaweed. The characterized fucans from Dictyotaceae are heterofucans containing mainly
G Klöck et al.
Applied microbiology and biotechnology, 40(5), 638-643 (1994-01-01)
Alginate is used as a matrix for immunoisolation of cells and tissues in vivo. We have demonstrated previously that commercial alginates contain various fractions of mitogenic impurities and that they can be removed by free flow electrophoresis. The use of
C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
A dye-binding assay for the spectrophotometric measurement of transparent exopolymer particles (TEP).
Passow U and Alldredge AL.
Limnology and Oceanography, 40(7), 1326-1335 (1995)
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