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A7219

L-Aspartic acid

Name: <SC>L</SC>-Aspartic acid
Brand: SIGMA

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Synonym(s):

(S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid

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About This Item

Linear Formula:

HO₂CCH₂CH(NH₂)CO₂H

CAS Number:

56-84-8

Molecular Weight:

133.10

NACRES:

NA.75

PubChem Substance ID:

24891191

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-291-6

MDL number:

MFCD00002616

Beilstein/REAXYS Number:

1723530

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Properties

biological source

non-animal source

Quality Segment

300

agency

meets EP testing specifications, meets USP testing specifications

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

1 M HCl: 100 mg/mL

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Grin2a(24409)

Description

General description

Aspartic acid(ASP)/aspartate, a non-essential amino acid, is naturally produced by mammals. ASP is one of the 20 building-block amino acids of proteins and has a one letter code, D. L-Aspartic acid can be manufactured industrially by an enzymatic process using the aspartase enzyme.

Application

L-Aspartic acid has been used:

as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats
as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR)
as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Global Trade Item Number

SKU	GTIN
A7219-100G	04061835568086
A7219-1KG	04061833383827