A7252
Ajmaline
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About This Item
Empirical Formula (Hill Notation):
C20H26N2O2
CAS Number:
Molecular Weight:
326.43
UNSPSC Code:
41116107
EC Number:
224-439-4
MDL number:
SMILES string
CCC1C(O)N2C3CC1C4C(O)C5(CC24)[C@H]3N(C)c6ccccc56
storage temp.
2-8°C
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Biochem/physiol Actions
Indole alkaloid from Rauwolfia serpentina that is a Class Ia antiarrhythmia compound. It blocks sodium channels in skeletal and cardiac muscle and cardiac HERG potassium channels in the open state but not in the closed state. Ajmaline administered intravenously prolongs the atrioventricular (AV) conduction times in the heart and has been used diagnostically to detect AV block and other cardiac abnormalities.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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