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A7631

(+)-Sodium L-ascorbate

Name: (+)-Sodium <SC>L</SC>-ascorbate
Brand: SIGMA

crystalline, ≥98%

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Synonym(s):

L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

Empirical Formula (Hill Notation):

C₆H₇NaO₆

CAS Number:

134-03-2

Molecular Weight:

198.11

Beilstein:

3767246

EC Number:

205-126-1

MDL number:

MFCD00082340

eCl@ss:

34058010

PubChem Substance ID:

24891261

NACRES:

NA.79

biological source

synthetic

Quality Level

300

Assay

≥98%

form

crystalline

technique(s)

HPLC: suitable

color

white to off-white

mp

220 °C (dec.) (lit.)

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

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Related Categories

Vitamins

General description

Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. L-Ascorbic acid is a reducing agent.

Application

(+)-Sodium L-ascorbate has been used:

as a component of cutting solution for storing brain slices of rats
as a component of patch pipette internal solution for imaging Ca²⁺ transients evoked by action potential in rat brain slices
as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

Biochem/physiol Actions

Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.

Caution

May darken in storage.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Imaging calcium concentration dynamics in small neuronal compartments

Yasuda R, et al.

Science's STKE : Signal Transduction Knowledge Environment, 219, pl5-pl5 (2004)

Exogenous ascorbic acid (vitamin C) increases resistance to salt stress and reduces lipid peroxidation

Shalata A and Neumann P M

Journal of Experimental Botany, 52(364), 2207-2211 (2001)

Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla

Patak P, et al.

Endocrine Research, 30(4), 871-875 (2004)

Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice

Suen RS, et al.

The American Journal of Pathology, 179(3), 1549-1559 (2011)

Reduction of graphene oxide via L-ascorbic acid.

Jiali Zhang et al.

Chemical communications (Cambridge, England), 46(7), 1112-1114 (2010-02-04)

We demonstrated that the individual graphene oxide sheets can be readily reduced under a mild condition using L-ascorbic acid (L-AA). This simple approach should find practical applications in large scale production of water soluble graphene.

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