Anti-Aflatoxin B₁ antibody produced in rabbit

Aflatoxin B₁ is the most abundant and significant member of the group, which includes B₂, B_2a, G₁, G_2a, M₁, M₂, P₁, Q1, aflatoxicol I (natural isomer), aflatoxicol II (unnatural isomer), tetrahydrodeoxy aflatoxin B1, and the unstable reactive B₁ (8,9)-epoxide.

Aflatoxins are highly carcinogenic.

Aflatoxins are highly toxic mycotoxins produced by the fungus Aspergillus. Aflatoxins are commonly found in various grains and peanut butter.

Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.

The antibody reacts with the B₁ aflatoxin and also recognizes aflatoxins G₁, B₂, and the KLH protein. No cross-reaction is observed with aflatoxins and B_2a, G₂, G_2a, M₁.

aflatoxin B₁-KLH.

Rabbit Anti-Aflatoxin B1 antibody has been used for the development of electrochemical immunosensors. The antibody has also been used in designing novel sandwich immunoassays. The product can also be used for capture ELISA at a dilution of 1:1,000.

Aflatoxin B₁ and its metabolites act as potent carcinogens, mutagens and teratogens. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.

Sensitivity range for this product is 0.005-20 ng/ml of aflatoxin B₁.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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