A8981
AS-252424
≥98% (HPLC), solid
Synonym(s):
5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C14H8FNO4S
CAS Number:
Molecular Weight:
305.28
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
assay
≥98% (HPLC)
form
solid
color
yellow
solubility
DMSO: >20 mg/mL
storage temp.
2-8°C
SMILES string
Oc1cc(F)ccc1-c2ccc(\C=C3\SC(=O)NC3=O)o2
InChI
1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6+
InChI key
OYYVWNDMOQPMGE-WUXMJOGZSA-N
Biochem/physiol Actions
AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor with IC50 = 30 nM in a mouse model.
AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
Discover Bioactive Small Molecules for Kinase Phosphatase Biology
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A8981-5MG | 04061832433813 |
| A8981-25MG | 04061832433806 |