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Merck
CN

A9074

2-Amino-2-methyl-1,3-propanediol

BioXtra, pH 10.0-12.0 (20 °C, 0.5 M in H2O), ≥99%

Synonym(s):

AMPD, Ammediol

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About This Item

Linear Formula:
(HOCH2)2C(NH2)CH3
CAS Number:
Molecular Weight:
105.14
EC Number:
204-100-7
UNSPSC Code:
12161700
PubChem Substance ID:
Beilstein/REAXYS Number:
635708
MDL number:
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vapor density

3.63 (vs air)

vapor pressure

~10 mmHg ( 152 °C)

product line

BioXtra

assay

≥99%

impurities

<0.005% Phosphorus (P), <0.1% Insoluble matter

ign. residue

<0.1%

pH

10.0-12.0 (20 °C, 0.5 M in H2O)

useful pH range

7.8-9.7

pKa (25 °C)

8.8

bp

151 °C/10 mmHg (lit.)

mp

100-110 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): <0.05%, sulfate (SO42-): <0.05%

cation traces

Al: <0.001%, Ca: <0.0005%, Cu: <0.0005%, Fe: <0.0005%, K: <0.005%, Mg: <0.0005%, NH4+: <0.05%, Na: <0.005%, Pb: <0.001%, Zn: <0.0005%

SMILES string

CC(N)(CO)CO

InChI

1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3

InChI key

UXFQFBNBSPQBJW-UHFFFAOYSA-N

Application

Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

>212.0 °F

flash_point_c

> 100 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Jung-Yeon Park et al.
Environmental science & technology, 37(8), 1670-1675 (2003-05-07)
Acid gas absorption technology is of great importance in these days for the prevention of global warming and the resulting worldwide climate change. More efficient process design and development for the removal of acid gases has become important, together with
Karen M O'Connor et al.
Journal of pharmaceutical sciences, 91(10), 2271-2281 (2002-09-13)
Dissolution of diclofenac from compressed discs containing mixtures of a diclofenac salt and a basic excipient, in various w/w ratios, was examined. Two diclofenac salts, diclofenac deanol (DDNL) and diclofenac tert-butylamine, and the basic excipient 2-amino-2-methyl-1,3-propanediol (AMPD) were examined. Inclusion
H Kikuchi et al.
The Tohoku journal of experimental medicine, 173(4), 391-397 (1994-08-01)
The method by MacQueen and Plaut was modified to devise simple microdetermination method of l-lactate which is applicable to deproteinized blood sample. Blood was deproteinized with addition of 25% (w/w) trichloroacetic acid (TCA), and 0.075 M 2-amino-2-methyl-1, 3-propanediole (AMPD) was