AC-0335A
Prostein (P501S, SLC45A3) (EP381) Rabbit Monoclonal Primary Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
monoclonal
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
Application:
IHC (p)
Citations:
-
biological source
rabbit
antibody form
Ig fraction of antiserum
clone
monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
General description
Prostein, also known as P501S, is encoded by the Solute carrier family 45, member 3 (SLC45A3) gene, an androgen-regulated gene and a prostate specific marker expressed in prostatic glandular cells. SLC45A3 is the second most common gene fusion partner in prostate cancers. SLC45A3-ERG and SLC45A3-ELK4 fusion transcripts have been detected in prostate cancer. Loss of prostein expression in SLC45A3-ERG tumors are significantly associated with high Gleason scores and poor clinical outcomes. Prostein immunoreactivity is seen in the majority of primary and metastatic prostate carcinomas. Staining for prostein in conjunction with PSA improves identification of prostatic origin in unknown primary lesions, when compared against prostein or PSA staining alone.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1%BSA and &< 0.1% Sodium Azide
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
For a copy of the IFU and CofA contact IVDorder@ABCAM.com
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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