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AV31654

Sigma-Aldrich

Anti-ESRRB antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
Anti-Estrogen-related receptor β
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

mol wt

56 kDa

species reactivity

human, mouse, horse, dog, bovine, rat, guinea pig

packaging

pkg of 100 μL buffered aqueous solution
pkg of 50 μg lyophilized powder

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_004443

UniProt accession no.

O95718

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ESRRB(2103)

General description

Estrogen-related-receptor β (Esrrb) is a member of the nuclear orphan receptor family that can induce cell differentiation in cultured mouse embryonic stem (ES) cells. Studies have reported that Esrrb can stimulate Oct4 transcription. This receptor can also regulate the pulripotency of ES cells.
Rabbit Anti-ESRRB antibody recognizes human, mouse, rat, bovine, and canine ESRRB.

Immunogen

Synthetic peptide directed towards the N terminal region of human ESRRB

Application

Rabbit Anti-ESRRB antibody can be used for western blot applications at a concentration of 0.5μg/ml.

Biochem/physiol Actions

ESRRB encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. Sequence Note: The sequence AF094517.1 is from a chimeric clone. Only the ESRRB sequence was propagated into this RefSeq record.

Sequence

Synthetic peptide located within the following region: RHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANG

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Lei Han et al.
Environmental toxicology, 39(1), 106-119 (2023-09-04)
Total flavonoids of Rhizoma drynariae (TFRD) is broadly used in the treatment of orthopedic diseases. Nevertheless, the effects and underlying mechanism of TFRD on tendon-bone healing after anterior cruciate ligament reconstruction (ACLR) remain unclear. The ACLR mouse model was established.
Xiaofei Zhang et al.
The Journal of biological chemistry, 283(51), 35825-35833 (2008-10-30)
The genetic program of embryonic stem (ES) cells is orchestrated by a core of transcription factors that has OCT4, SOX2, and NANOG as master regulators. Protein levels of these core factors are tightly controlled by autoregulatory and feed-forward transcriptional mechanisms

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