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Merck
CN

AV31926

Anti-RAX (AB2) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-RX, Anti-Retina and anterior neural fold homeobox

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-RAX (AB2) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

37 kDa

species reactivity

horse, mouse, human, guinea pig, bovine, rat

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_038463

UniProt accession no.

Q9Y2V3

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Gene Information

human ... RAX(30062)

Application

Rabbit Anti-RAX (AB2) antibody can be used for western blot assays at a concentration of 0.5μg/ml.
Rabbit polyclonal anti-RAX (AB2) antibody is used to tag retina and anterior neural fold homeobox for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of retina and anterior neural fold homeobox in eye field/retinal development and eye pathologies such as microphthalmia and anophthalmia.

Biochem/physiol Actions

Retinal Homeobox Protein Rx (RAX) is a member of homeobox family of transcription factors. Mutations mouse and fish RAX lead to defects in retinal development and result in animal models of anophthalmia.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Rabbit polyclonal anti-RAX (AB2) antibody reacts with bovine, canine, human, mouse, and rat retina and anterior neural fold homeobox factors.
Retina and anterior neural fold homeobox (RAX) is a paired-type homeobox gene expressed in the anterior neural fold and developing retina. RAX is involved in defining the eye field during early development wherein it participates in regulation of the proliferation and/or differentiation of retinal cells. Defects in RAX have been linked to the eye pathologies microphthalmia and anophthalmia.

Immunogen

Synthetic peptide directed towards the N terminal region of human RAX

Other Notes

Synthetic peptide located within the following region: MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGT

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC21438

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