Anti-HOXD3 (AB1) antibody produced in rabbit

HoxD3 is a homeobox transcription factor that activates collagen synthesis and angiogenesis and can accelerate wound healing in mice. HOXD3 (HOX4A) has also been implicated in cell adhesion.
Rabbit Anti-HOXD3 (AB1) antibody recognizes canine, human, mouse, rat, and bovine HOXD3.

Synthetic peptide directed towards the middle region of human HOXD3

Rabbit Anti-HOXD3 (AB1) antibody can be used for immunohistochemical assays at a concentration of 4-8μg/ml, using paraffin-embedded tissues. The antibody can also be used for western blot assays 1-2μg/ml.

HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5′ end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Synthetic peptide located within the following region: AHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPS

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