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AV32069

Sigma-Aldrich

Anti-PBX2 (AB2) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-G17, Anti-HOX12, Anti-PBX2MHC, Anti-Pre-B-cell leukemia homeobox 2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

46 kDa

species reactivity

human, guinea pig, horse, mouse, rat

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_002577

UniProt accession no.

P40425

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PBX2(5089)

General description

PBX2 is a homeobox transcription factor that shares homology with the human proto-oncogene, PBX1. Studies have reported that PBX2 forms triple complexes with HOXA9 and MEIS1 in myeloid cells.
Rabbit Anti-PBX2 (AB2) antibody recognizes pig, human, mouse, and rat PBX2.

Immunogen

Synthetic peptide directed towards the N terminal region of human PBX2

Application

Rabbit Anti-PBX2 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml.

Biochem/physiol Actions

PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

Sequence

Synthetic peptide located within the following region: MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGK

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC1557

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