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Merck
CN

AV32383

Anti-SIX6 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Sine oculis homeobox homolog 6 (Drosophila)

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-SIX6 antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

28 kDa

species reactivity

guinea pig, bovine, mouse, human, dog, rat, sheep, horse, rabbit

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_031400

UniProt accession no.

O95475

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Gene Information

human ... SIX6(4990)

Application

Rabbit Anti-SIX6 antibody can be used for western blot (0.5μg/ml) and IHC (4-8μg/ml) applications.

Biochem/physiol Actions

SIX6 is a member of SIX family. It is the homologue of the chick Six6(Optx2) gene. SIX6 is closely related to SIX3 and is expressed in the developing and adult human retina.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

SIX6 is a homeobox protein and may regulate eye development. Studies have linked homozygous truncations in SIX6 to complex microphthalmia in humans.
Rabbit Anti-SIX6 antibody recognizes chicken, bovine, canine, zebrafish, human, mouse, rat, and pig SIX6.

Immunogen

Synthetic peptide directed towards the N terminal region of human SIX6

Other Notes

Synthetic peptide located within the following region: PAACEALNKNESVLRARAIVAFHGGNYRELYHILENHKFTKESHAKLQAL

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC1859

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Homozygous truncation of SIX6 causes complex microphthalmia in humans.
M A Aldahmesh et al.
Clinical genetics, 84(2), 198-199 (2012-11-22)

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