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Merck
CN

B1434

BMP7, human

>95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

Synonym(s):

Bone Morphogenetic Protein 7 human, BMP-7, OP-1, Osteogenic protein 1

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Biological source:
human
Recombinant:
expressed in CHO cells
Assay:
>95% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
monomer calculated mol wt 15.7 kDa, 18-20 kDa by SDS-PAGE (reducing), 30-40 kDa by SDS-PAGE (non-reducing)
Impurities:
endotoxin, tested
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Product Name

Bone Morphogenetic Protein 7 human, >95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

biological source

human

Quality Segment

recombinant

expressed in CHO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.2-0.6 μg/mL ED50

mol wt

monomer calculated mol wt 15.7 kDa, 18-20 kDa by SDS-PAGE (reducing), 30-40 kDa by SDS-PAGE (non-reducing)

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... BMP7(655)

Biochem/physiol Actions

Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

Physical form

Lyophilized from 50.0 μl of a 0.2 μm filtered solution in 35% acetonitrile, 0.1% TFA containing 50 μg bovine serum albumin per 1μg of cytokine.

Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production using mouse ATDC-5 chondrogenic cells.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

wgk

WGK 2



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