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B1436

BAX Inhibiting Peptide V5

Name: BAX Inhibiting Peptide V5
Brand: SIGMA

≥97% (HPLC), lyophilized powder

Synonym(s):

BIP-V5

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About This Item

Empirical Formula (Hill Notation):

C₂₇H₅₀N₆O₆S

CAS Number:

579492-81-2

Molecular Weight:

586.79

UNSPSC Code:

12352200

NACRES:

NA.32

MDL number:

MFCD04974826

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Properties

Quality Segment

200

assay

≥97% (HPLC)

form

lyophilized powder

storage temp.

−20°C

SMILES string

S(CC[C@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)C

InChI

1S/C27H50N6O6S/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39)/t18-,19-,20-,21-,22-/m0/s1

InChI key

NHMUTADCTDDWPV-YFNVTMOMSA-N

Description

Biochem/physiol Actions

BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.

Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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