B1502
Brain Extract from bovine brain
Type I, Folch Fraction I
Synonym(s):
Brain Extract from Bovine
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352211
biological source
bovine brain
type
Type I
form
powder
lipid type
phosphoglycerides
storage temp.
−20°C
Quality Level
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General description
Brain extract has lipids, especially polyunsaturated fatty acids (PUFAs) at high level. Extract from substantia niagra and the striatum has high amount of iron.
Application
Brain Extract from bovine brain has been used:
- to prepare small unilamellar vesicles
- in lipid binding assay
- to aid the recovery of phosphoinositides and also to terminate the reaction in phosphatidylinositol 5-phosphate (PtdIns5P) and PtdIns4P assay
- in liposome and protein self-aggregation assays
Biochem/physiol Actions
Brain lipids are involved in cellular signal transduction, membrane organization, trafficking protein modification, interactions and energy storage.
Packaging
Sealed ampule.
Other Notes
Contains phosphatidylinositol phosphatidylserine,other brain lipids.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Qing Lu et al.
Molecular biology of the cell, 22(22), 4268-4278 (2011-10-04)
Myosin X (MyoX) is an unconventional myosin that is known to induce the formation and elongation of filopodia in many cell types. MyoX-induced filopodial induction requires the three PH domains in its tail region, although with unknown underlying molecular mechanisms.
Measurement of phosphoinositides in the zebrafish Danio rerio
Jones DR, et al.
Nature Protocols, 8(6), 1058-1058 (2013)
Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity
Jin W, et al.
The Journal of Neuroscience, 26, 2380-2390 (2006)
Cholesterol and Fat Metabolism in Alzheimer?s Disease
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders, 161-193 (2017)
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D
Freye-MC, et al.
Biochemistry, 42(3), 620-630 (2003)
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