B2390
(±)-Brompheniramine maleate salt
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About This Item
Empirical Formula (Hill Notation):
C16H19BrN2 · C4H4O4
CAS Number:
Molecular Weight:
435.31
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
SMILES string
OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccc(Br)cc1)c2ccccn2
InChI
1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
SRGKFVAASLQVBO-BTJKTKAUSA-N
Gene Information
human ... HRH1(3269)
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Biochem/physiol Actions
Antihistamine; H1 histamine receptor antagonist.
Signal Word
Warning
Hazard Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Ana Carolina Valinoti et al.
International journal of paediatric dentistry, 21(2), 141-150 (2010-10-22)
To evaluate the effect of acidic medicines (Klaricid(®), Claritin(®), and Dimetapp(®)) on surface enamel in vitro. Enamel blocks (n=104) were randomly distributed into two groups: G1 (pH-cycling simulating physiological oral conditions) and G2 (erosive conditions). Each group was divided into
Laura R Sadofsky et al.
Experimental lung research, 34(10), 681-693 (2008-12-17)
American guidelines, unlike European guidelines, support the use of antihistamines as a first line of treatment for some causes of chronic cough. Transient receptor potential vanilloid-1 (TRPV1) is an ion channel activated by the tussive agents capsaicin, resiniferatoxin, and protons.
Ahmed S Zidan et al.
Journal of pharmaceutical sciences, 101(4), 1450-1461 (2012-01-04)
The objective of the current study was to evaluate the performance of Raman and near-infrared (NIR) techniques combined with chemometrics in characterizing the critical quality attributes of brompheniramine (BP)-tannate complexes. Seven complexes were prepared and evaluated for chemical interactions, solubilities
Silvia Tardioli et al.
The journal of physical chemistry. B, 116(24), 7033-7039 (2012-05-23)
Binding of the antihistamine drug brompheniramine (BPA) to human serum albumin (HSA) is studied by measuring quenching of the fluorescence and room temperature phosphorescence (RTP) of tryptophan. The modified Stern-Volmer equation was used to derive association constants and accessible fractions
J Sörbo et al.
International journal of experimental pathology, 75(1), 43-50 (1994-02-01)
The activation of mast-cells in situ induces angiogenesis in normally vascularized, adult mammalian tissue. Since the secreting mast-cell characteristically releases histamine, we studied the possible role of histamine in the outcome of mast-cell mediated angiogenesis using the rat mesenteric window
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