B2517
6-Biopterin
≥97%
Synonym(s):
(1’R,2’S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin
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About This Item
Empirical Formula (Hill Notation):
C9H11N5O3
CAS Number:
Molecular Weight:
237.22
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
EC Number:
244-807-8
Beilstein/REAXYS Number:
87860
MDL number:
Form:
powder
Assay:
≥97%
Solubility:
1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow
Biological source:
synthetic
biological source
synthetic
Quality Level
assay
≥97%
form
powder
solubility
1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow
storage temp.
2-8°C
SMILES string
C[C@H](O)[C@H](O)c1cnc2NC(N)=NC(=O)c2n1
InChI
1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1
InChI key
LHQIJBMDNUYRAM-DZSWIPIPSA-N
Application
6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Siew Ling Choy et al.
Scientific reports, 7(1), 9472-9472 (2017-08-27)
Intracellular pathogens belonging to the genus Leishmania have developed effective strategies that enable them to survive within host immune cells. Immunostimulatory compounds that counteract such immunological escape mechanisms represent promising treatment options for diseases. Here, we demonstrate that a lipopeptidephosphoglycan
Nathalie Isorce et al.
Bio-protocol, 10(9), e3598-e3598 (2021-03-05)
Many RNA viruses are found in protozoan parasites. They can be responsible for more serious pathology or treatment failure. For the detection of viral double-stranded RNA (dsRNA), sequence-dependent and -independent methods are available, such as quantitative real-time PCR and immunofluorescence
Emma L DeWalt et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 1), 74-81 (2013-01-01)
Polarization-resolved second-harmonic generation (PR-SHG) microscopy is described and applied to identify the presence of multiple crystallographic domains within protein-crystal conglomerates, which was confirmed by synchrotron X-ray diffraction. Principal component analysis (PCA) of PR-SHG images resulted in principal component 2 (PC2)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B2517-5MG | 04061833426869 |
| B2517-25MG | 04061833426852 |
| B2517-50MG | 04061833045398 |