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B2557

8-Bromo-2′-monobutyryladenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer

Name: 8-Bromo-2′-monobutyryladenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer
Brand: SIGMA

>97% (HPLC), solid

Synonym(s):

Rp-8-Br-MB-cAMPS

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₆BrN₅O₆PSNa

Molecular Weight:

516.24

NACRES:

NA.77

PubChem Substance ID:

329773204

UNSPSC Code:

41106305

MDL number:

MFCD04113730

Assay:

>97% (HPLC)

Form:

solid

Quality level:

200

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Quality Level

200

assay

>97% (HPLC)

form

solid

packaging

vial of 5 μmol (2.5 mg solid)

solubility

water: soluble

storage temp.

−20°C

SMILES string

CCCC(=O)O[C@@H]1[C@@H]2O[P@](O)(=S)OC[C@H]2O[C@H]1n3c(Br)nc4c(N)ncnc34

InChI

1S/C14H17BrN5O6PS/c1-2-3-7(21)25-10-9-6(4-23-27(22,28)26-9)24-13(10)20-12-8(19-14(20)15)11(16)17-5-18-12/h5-6,9-10,13H,2-4H2,1H3,(H,22,28)(H2,16,17,18)/t6-,9-,10-,13-,27-/m1/s1

InChI key

KWTXVSKODFLFLA-WJCFKVOZSA-N

Related Categories

Bioactive Small Molecule Inhibitors

Application

Lipophilic precursor that is more lipophilic and membrane-permeable compared to Rp-8-Br-cAMPS.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Modulation of Ca2+ channels by cyclic nucleotide cross activation of opposing protein kinases in rabbit portal vein.

V Ruiz-Velasco et al.

Circulation research, 82(5), 557-565 (1998-04-07)

Cyclic nucleotides are known to modify voltage-gated (L-type) Ca2+ channel activity in vascular smooth muscle cells, but the exact mechanism(s) underlying these effects is not well defined. The purpose of the present study was to investigate the modulatory role of

Global Trade Item Number

SKU	GTIN
B2557-1VL	04061838168818

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