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B2680

BMP4, human

Name: BMP4, human
Brand: SIGMA

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

Synonym(s):

Bone Morphogenetic Protein 4 human, BMP-4

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About This Item

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD01867024

Biological source:

human

Recombinant:

expressed in NSO cells

Assay:

>95% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

monomer calculated mol wt 13 kDa, ~22 kDa by SDS-PAGE

Impurities:

<0.01 EU/μg Endotoxin level (LAL test)

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Properties

Product Name

Bone Morphogenetic Protein 4 human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

biological source

human

Quality Segment

200

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.70-7.00 ng/mL ED₅₀

mol wt

monomer calculated mol wt 13 kDa, ~22 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

technique(s)

cell culture | mammalian: suitable

impurities

<0.01 EU/μg Endotoxin level (LAL test)

UniProt accession no.

P12644

storage temp.

−20°C

Gene Information

human ... BMP4(652)

Description

Biochem/physiol Actions

Cellular responses to BMP-4 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF A by osteoblasts. Mature human and mouse BMP-4 demonstrates 98% and 100% homology, respectively, to mature rat BMP-4.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 50 μg of bovine serum albumin per 1 μg of cytokine.

Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production by C2C12 myoblasts.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c