Merck
CN
All Photos(1)

Documents

B2754

Sigma-Aldrich

Betaine monohydrate

≥99%

Sign Into View Organizational & Contract Pricing
All Photos(1)
Linear Formula:
(CH3)3N+CH2COO- · H2O
CAS Number:
590-47-6
Molecular Weight:
135.16
Beilstein:
3626258
EC Number:
209-684-7
MDL number:
MFCD00150010
PubChem Substance ID:
24891670
NACRES:
NA.83

biological source

synthetic

Assay

≥99%

form

powder or crystals

solubility

water: 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

O.C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2

InChI key

NJZRLXNBGZBREL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Betaine is a zwitterionic quaternary ammonium compound and is mainly present in animals, microorganisms and plants. It is one of the main constituent of several food items like wheat, shellfish, spinach and sugar beets. It is also termed as trimethylglycine, lycine, glycine betaine and oxyneurine. Betaine is a methyl derivative of glycine. It has a molecular mass of 117.2.

Application

Betaine monohydrate has been used:
  • in the preparation of KLA buffer to perform polymerase chain reaction (PCR)
  • to study the its effects on Km and Vmax of human aldose reductase
  • to study its effects on the growth of A549 lung cancer both in vitro and in vivo

Biochem/physiol Actions

Betaine, as an osmolyte helps to guard the cells, proteins and enzymes from environmental stress. It also acts as a methyl donor to involve in the methionine cycle.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Anirban Purohit et al.
Biophysical journal, 120(1), 73-85 (2020-11-23)
Sliding clamps are oligomeric ring-shaped proteins that increase the efficiency of DNA replication. The stability of the Escherichia coli β-clamp, a homodimer, is particularly remarkable. The dissociation equilibrium constant of the β-clamp is of the order of 10 pM in
Study of the effects of betaine and/or C-phycocyanin on the growth of lung cancer A549 cells in vitro and in vivo
Bingula R, et al.
Journal of Oncology, 2016 (2016)
Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis.
Surendran K, et al.
Journal of the American Society of Nephrology, 16(8), 2373-2384 (2005)
Factors affecting counteraction by methylamines of urea effects on aldose reductase
Burg MB, et al.
Proceedings of the National Academy of Sciences of the USA, 96(11), 6517-6522 (1999)
Stuart A S Craig
The American journal of clinical nutrition, 80(3), 539-549 (2004-08-24)
Betaine is distributed widely in animals, plants, and microorganisms, and rich dietary sources include seafood, especially marine invertebrates ( approximately 1%); wheat germ or bran ( approximately 1%); and spinach ( approximately 0.7%). The principal physiologic role of betaine is
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service