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About This Item

Empirical Formula (Hill Notation):
C19H18O9
CAS Number:
Molecular Weight:
390.34
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
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Quality Level

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

COC(=O)c1cc(OC)c2OCOc2c1-c3c(CO)cc(OC)c4OCOc34

InChI

1S/C19H18O9/c1-22-11-4-9(6-20)13(17-15(11)25-7-27-17)14-10(19(21)24-3)5-12(23-2)16-18(14)28-8-26-16/h4-5,20H,6-8H2,1-3H3

InChI key

KXMTXZACPVCDMH-UHFFFAOYSA-N

General description

Bicyclol has anti-inflammatory properties and enhances the prognosis of kidney transplantation. It is involved in the removal of reactive oxygen species and modulates cytokine secretion.

Biochem/physiol Actions

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C.
Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. The drug appears to protect against liver injury in animals. Recently it was reported that bicyclol induce the expression of hepatic HSP27 and HSP70, and thus consequently inhibits the transcription factor NF-?B-mediated apoptosis and necrosis in liver tissue. It appears that bicyclol induces hepatic HSP27 and HSP70 expression through activating transcription of HSPs genes.

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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