B352-05
Bovine Pulmonary Artery Smooth Muscle Cells: BPASMC (Cryovial)
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About This Item
NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
bovine pulmonary artery (tunica intima and media)
Growth mode:
Adherent
Morphology:
smooth muscle
Relevant disease(s):
cardiovascular diseases
biological source
bovine pulmonary artery (tunica intima and media)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 60
morphology
smooth muscle
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
General description
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BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013).
Characterization: positive for smooth muscle cell specific alpha-actin expression.
BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013).
Characterization: positive for smooth muscle cell specific alpha-actin expression.
Application
cell growth, signaling, receptor transactivation and suppression, vascular remodeling
Biochem/physiol Actions
Artery
Preparation Note
- 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 16 doublings
Please refer to the BPASMC Culture Protocol.
Other Notes
Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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