Key Documents

View All Documentation

B4261

Biocytin

Name: Biocytin
Brand: SIGMA

≥98% (TLC), suitable for drug transporter assays

Synonym(s):

Bct, N_ε-(+)-Biotinyl-L-lysine

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₆H₂₈N₄O₄S

CAS Number:

576-19-2

Molecular Weight:

372.48

NACRES:

NA.26

PubChem Substance ID:

24891762

UNSPSC Code:

12352209

MDL number:

MFCD00077319

Beilstein/REAXYS Number:

97197

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Product Name

Biocytin, ≥98% (TLC)

Quality Level

200

assay

≥98% (TLC)

form

powder

optical activity

[α]20/D +53°, c = 1.05% in 0.1 M NaOH(lit.)

technique(s)

drug transporter assay: suitable

color

white to off-white

mp

~245 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C16H28N4O4S/c17-10(15(22)23)5-3-4-8-18-13(21)7-2-1-6-12-14-11(9-25-12)19-16(24)20-14/h10-12,14H,1-9,17H2,(H,18,21)(H,22,23)(H2,19,20,24)/t10-,11-,12-,14-/m0/s1

InChI key

BAQMYDQNMFBZNA-MNXVOIDGSA-N

Related Categories

Biochemicals

Cell Culture Supplements & Reagents

Amino Acids – Building Blocks of Life Science

Application

Biocytin is used as a substrate to study the specificity and kinetics of biotinidase(s), to measure biotinidase deficiency and as a model compound to study various uptake mechanisms of cells and tissues. Biocytin has been used to label neurons, medium spiny neurons and optic nerves.

Biochem/physiol Actions

Biocytin is an adduct of lysine and biotin. It is hydrolyzed by biotinidase, which acts on peptide-incorporated biotin or free biotin. Biocytin acts as a coenzyme.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy.

Rui Tian et al.

Theranostics, 8(3), 735-745 (2018-01-19)

Purpose: Radionuclide therapy directed against tumors that express somatostatin receptors (SSTRs) has proven effective for the treatment of advanced, low- to intermediate-grade neuroendocrine tumors in the clinic. In clinical usage, somatostatin peptide-based analogs, labeled with therapeutic radionuclides, provide an overall

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury.

Jeanne T Paz et al.

Nature neuroscience, 16(1), 64-70 (2012-11-13)

Cerebrocortical injuries such as stroke are a major source of disability. Maladaptive consequences can result from post-injury local reorganization of cortical circuits. For example, epilepsy is a common sequela of cortical stroke, but the mechanisms responsible for seizures following cortical

Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B.

Vishwa Mohan et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(32), 6233-6250 (2019-06-12)

Dendritic spines in the developing mammalian neocortex are initially overproduced and then eliminated during adolescence to achieve appropriate levels of excitation in mature networks. We show here that the L1 family cell adhesion molecule Close Homolog of L1 (CHL1) and

Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish

Chen Tian

Investigative Ophthalmology & Visual Science, 57(4) (2016)

Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson?s disease

William A

Neurobiology of Disease (2014)

View All Related Papers

Global Trade Item Number

SKU	GTIN
B4261-25MG	04061833429518
B4261-5MG	04061832415215
B4261-50MG	04061833429525
B4261-250MG	04061833429464
B4261-100MG	04061833429457

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service