Skip to Content
Merck
CN

Key Documents

View All Documentation

B4311

BF-170 hydrochloride

≥98% (HPLC), solid

Synonym(s):

2-(4-aminophenyl)quinoline hydrochloride, NSC 168387 hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C15H12N2 · HCl
CAS Number:
22191-97-5
Molecular Weight:
256.73
NACRES:
NA.77
PubChem Substance ID:
24891766
UNSPSC Code:
12352200
MDL number:
MFCD08705340
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
desiccated, protect from light, under inert gas
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated, protect from light, under inert gas

color

orange

solubility

H2O: 10 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].Nc1ccc(cc1)-c2ccc3ccccc3n2

InChI

1S/C15H12N2.ClH/c16-13-8-5-12(6-9-13)15-10-7-11-3-1-2-4-14(11)17-15;/h1-10H,16H2;1H

InChI key

UYYPMQOFLJHJAW-UHFFFAOYSA-N

Biochem/physiol Actions

BF-170 is a new probe for neurofibrillary tangles (tau fibrils) with greater binding affinity to tau than to Aβ fibrils.
BF-170 is a new probe for neurofibrillary tangles (tau fibrils). It exhibits greater binding affinity to tau than to Aβ fibrils, EC50 = 221 nM vs. EC50 = 786 nM (Ki for Aβ > 5,000 nM). BF-170 demonstrates fast clearance from the brain; clearly visualizes neurofibrillary tangles, neuropil threads, and paired helical filament-type neuritis. BF-70 may become one of the candidate compounds for in vivo imaging of tau pathology associated with Alzheimer′s disease and is a useful tool in distinguishing among tau and Aβ fibrils specifically in AD.

Disclaimer

Product is air sensitive, store under inert gas.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
046K46021
046K4602

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
B4311-5MG04061832977096
B4311-25MG04061832977089

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service