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B5057

7-Benzyloxy-4-trifluoromethylcoumarin

Name: 7-Benzyloxy-4-trifluoromethylcoumarin
Brand: SIGMA

≥99% (HPLC), solid

Synonym(s):

7-BFC

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₁₁F₃O₃

Molecular Weight:

320.26

UNSPSC Code:

12161501

PubChem Substance ID:

24891807

NACRES:

NA.47

MDL number:

MFCD01564466

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Properties

Product Name

7-Benzyloxy-4-trifluoromethylcoumarin, ≥99% (HPLC), solid

Quality Segment

100

assay

≥99% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12

InChI

1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2

InChI key

WVKLERKKJXUPIK-UHFFFAOYSA-N

Gene Information

rat ... Maoa(29253), Maob(25750)

Description

Application

7-Benzyloxy-4-trifluoromethylcoumarin has been used:

in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
in O-dealkylation reaction to determine the activity of CYP3A
to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)

Biochem/physiol Actions

Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.

Legal Information

Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.

pictograms

GHS07

signalword

Warning

hcodes

H302 + H312 + H332

pcodes

P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c