Skip to Content
Merck
CN

B6929

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt

≥95%

Synonym(s):

des(Arg10, Leu9)-Kallidin

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C47H75N13O11
Molecular Weight:
998.18
NACRES:
NA.32
PubChem Substance ID:
329773287
UNSPSC Code:
12352203
MDL number:
MFCD00274007

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt, ≥95%

InChI

1S/C47H75N13O11/c1-28(2)24-33(46(70)71)56-42(66)36-17-10-21-58(36)44(68)34(27-61)57-40(64)32(25-29-12-4-3-5-13-29)54-38(62)26-53-41(65)35-16-9-22-59(35)45(69)37-18-11-23-60(37)43(67)31(15-8-20-52-47(50)51)55-39(63)30(49)14-6-7-19-48/h3-5,12-13,28,30-37,61H,6-11,14-27,48-49H2,1-2H3,(H,53,65)(H,54,62)(H,55,63)(H,56,66)(H,57,64)(H,70,71)(H4,50,51,52)/t30-,31-,32-,33-,34-,35-,36-,37-/m0/s1

SMILES string

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCCN)C(O)=O

InChI key

AGTPZUQKOYEAOH-MDKUUQCZSA-N

assay

≥95%

form

powder

storage temp.

−20°C

Quality Level

200

Gene Information

human ... BDKRB1(623)
mouse ... BDKRB1(12061)
rat ... BDKRB1(81509)

Biochem/physiol Actions

B1 bradykinin receptor antagonist.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCG3832
BCBZ2878
BCBM1666V
BCBJ0208V
BCBG5097V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

T MacNeil et al.
Canadian journal of physiology and pharmacology, 75(6), 735-740 (1997-06-01)
We developed a functional assay to evaluate the activity of kinin peptides at the human and mouse bradykinin (BK) B1 receptors. The photoprotein aequorin expressed in 293-AEQ17 cells was used to measure calcium mobilization due to activation of the human
S P Zhang et al.
Life sciences, 62(25), 2303-2314 (1998-07-03)
Bradykinin (BK) receptors are involved in pain and inflammation. Two BK receptor subtypes, B1 and B2, have been defined based on their pharmacological properties. Both B1 and B2 receptors are G-protein coupled membrane receptors. B1 receptors are present in smooth
Ji-Zhe Jin et al.
Acta pharmacologica Sinica, 41(12), 1597-1608 (2020-04-18)
Tissue kallikrein has protective function against various types of injury. In this study, we investigated whether exogenous pancreatic kininogenase (PK) conferred renoprotection in a rat model of unilateral ureteral obstruction (UUO) and H2O2-treated HK-2 cells in vitro. SD rats were
J G Menke et al.
The Journal of biological chemistry, 269(34), 21583-21586 (1994-08-26)
A cDNA clone encoding a human B1 bradykinin receptor was isolated from a human embryonic lung fibroblast cDNA library by expression cloning. The photoprotein aequorin was utilized as an indicator of the ability of the B1 receptor agonist [des-Arg10]kallidin to
Man Zhang et al.
American journal of physiology. Cell physiology, 296(6), C1364-C1372 (2009-04-03)
Bradykinin (BK) is an endogenous peptide with diverse biological actions and is considered to be an important mediator of the inflammatory response in both the peripheral and the central nervous systems. BK has attracted recent interest as a potential mediator

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service