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Merck
CN

B7188

Blonanserin

≥98% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C23H30FN3
CAS Number:
132810-10-7
Molecular Weight:
367.50
NACRES:
NA.77
PubChem Substance ID:
329773292
UNSPSC Code:
12352200
MDL number:
MFCD00893838

Key Documents

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Product Name

Blonanserin, ≥98% (HPLC)

InChI key

XVGOZDAJGBALKS-UHFFFAOYSA-N

SMILES string

CCN1CCN(CC1)c2cc(-c3ccc(F)cc3)c4CCCCCCc4n2

InChI

1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥10 mg/mL

originator

Dainippon Sumitomo

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

Blonanserin is a D2/5-HT2 receptor antagonist; atypical antipsychotic.

Features and Benefits

This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H413

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000447291
0000447291
0000421729
0000421731
0000421729

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Case of delirium complicated with pneumonia that improved with blonanserin administration.
Hidehiro Andoh et al.
Psychiatry and clinical neurosciences, 64(5), 588-589 (2010-10-07)
Neuroleptic malignant syndrome induced by blonanserin.
Keiko Ohoyama et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(1), E13-E13 (2011-02-10)
Hidenobu Suzuki et al.
Psychiatry and clinical neurosciences, 66(2), 146-152 (2012-02-23)
Blonanserin is a second-generation antipsychotic that was developed in Japan. We investigated the relationships between plasma concentration, the plasma anti-5-HT(2A) activity/anti-D₂ activity (S/D) ratio and extrapyramidal symptoms (EPS) in blonanserin dosing. The subjects were 29 outpatients with schizophrenia. We assessed
Tadashi Ogawa et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 26(10), 1099-1102 (2010-10-19)
A rapid and sensitive method for analysis of blonanserin in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry is presented. After pretreatment of a plasma sample by solid-phase extraction, blonanserin was analyzed by the system with a C(18) column. This
Blonanserin for the treatment of delirium patients at an emergency medical care center: an open-label study.
Koji Kato et al.
Asian journal of psychiatry, 6(2), 182-183 (2013-03-08)
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