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B7686

1(S),9(R)-(−)-Bicuculline methchloride

Name: 1(S),9(R)-(&#8722;)-Bicuculline methchloride
Brand: SIGMA

≥97% (HPLC), GABAA receptor antagonist, powder

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About This Item

Linear Formula:

C₂₁H₂₀NO₆Cl

CAS Number:

38641-83-7

Molecular Weight:

417.84

UNSPSC Code:

12352200

PubChem Substance ID:

329773300

NACRES:

NA.77

MDL number:

MFCD00055233

Assay:

≥97% (HPLC)

Form:

powder

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Properties

Product Name

1(S),9(R)-(−)-Bicuculline methchloride, ≥97% (HPLC), powder

Quality Segment

100

assay

≥97% (HPLC)

form

powder

solubility

H₂O: >10 mg/mL

storage temp.

2-8°C

SMILES string

[Cl-].C[N+]1(C)CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45

InChI

1S/C21H20NO6.ClH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1

InChI key

RLJKFAMYSYWMND-GRTNUQQKSA-M

Description

Biochem/physiol Actions

1(S),9(R)-(−)-Bicuculline methchloride is a GABA_A receptor antagonist, which blocks Ca²⁺-activated potassium (SK) channels.

Features and Benefits

This compound is featured on the GABAA Receptors and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Articles

GABAA Receptors

We offer many products related to GABAA receptors for your research needs.

Potassium Channels

We offer many products related to potassium channels for your research needs.

DISCOVER Bioactive Small Molecules for Neuroscience

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Global Trade Item Number

SKU	GTIN
B7686-25MG	04061833442067
B7686-125MG	04061832079424