Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
UNSPSC Code:
41105331
eCl@ss:
32160703
manufacturer/tradename
BPS Bioscience
storage temp.
-65 to -96°C
General description
HDAC assay developer is an essential reagent for signal generation in HDAC assays performed with any of BPS Bioscience′s HDAC fluorimetric substrates or assay kits. An appropriate fluorimetric substrate, comprising an acetylated lysine side chain, is first incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.). Deacetylation of the substrate sensitizes it so that, in a second step, treatment with the HDAC assay developer produces a fluorophore. Trichostatin A is included as an ′inhibitor stop′ for class I and II HDACs.Datasheet
Application
Study of HDAC kinetics, regulation and inhibitor sensitivity. Ideal for drug discovery and HTS applications and cell-based HDAC assays.
Datasheet and Protocols may be found here.
Datasheet and Protocols may be found here.
Preparation Note
A 2x concentrate. Product is to be used (undiluted) at 1:1 ratio with HDAC reaction.
Analysis Note
Avoid freeze/thaw cycles. Use product undiluted.
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.