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C0128

α-Chloralose

Name: α-Chloralose
Brand: SIGMA

Synonym(s):

1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose, Anhydro-D-glucochloral, Chloralose

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₁Cl₃O₆

CAS Number:

15879-93-3

Molecular Weight:

309.53

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

24892236

EC Number:

240-016-7

Beilstein/REAXYS Number:

85418

MDL number:

MFCD00005542

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Properties

form

powder

Quality Level

100

impurities

≤20% β-anomer

color

white to off-white

solubility

ethanol: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow (or yellow-brown)

SMILES string

OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl

InChI

1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1

InChI key

OJYGBLRPYBAHRT-IPQSZEQASA-N

Description

Application

α-Chloralose has been used as anesthetic in surgical preparations.

Biochem/physiol Actions

α-Chloralose is used as an immobilizing agent. It is mostly used in studies, which involves autonomic reflexes. α-Chloralose is a sedative hypnotic. It has high significance as anesthetic for laboratory animals.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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pictograms

GHS06,GHS09

signalword

Danger

hcodes

H301,H332,H336,H410

pcodes

P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

涉药品监管产品

危险化学品

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Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats

Donnelly WT, et al.

Experimental Physiology, 101(7), 946-961 (2016)

Preparation of water-soluble compounds by covalent attachment of solubilizing moieties

The Practice of Medicinal Chemistry, 767-785 (2008)

Activation of serotonergic neurons in the medullary caudal raphe shortens the laryngeal chemoreflex in anaesthetized neonatal rats