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C0235

Z-Ala-Ala-Asp(OMe)-chloromethyl ketone

≥98% (TLC), solid

Synonym(s):

Z-AAD(OMe)-CMK

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About This Item

Empirical Formula (Hill Notation):
C20H26N3O7Cl
Molecular Weight:
455.89
UNSPSC Code:
12352200
MDL number:
MFCD03452874
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assay

≥98% (TLC)

form

solid

storage temp.

−20°C

SMILES string

COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)CCl

Application

Cell permeable Granzyme B inhibitor peptide.

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
024K0820
071K1763

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Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors.
D M Segal et al.
Biochemistry, 10(20), 3728-3738 (1971-09-28)